Using Veeam backup/snapshot is very common with Caché and IRIS, and when using the snapshot process there are a couple things to be aware of:
1. Make sure you are NOT including the VM's memory state as this will have a long impact to VM stun times.
2. Make sure you are current with VMware vSphere patches as there are some known issues with snapshot performance and data consistency in older versions of vSphere. I would recommend being on at least vSphere 6.7 or above.
3. You need to make sure your journal disk is on a different VMDK than any of your CACHE.DATs and CACHE.WIJ especially after you the thaw the instance because a large burst of writes may happen and cause IO to flood/serialize the device and potentially block or slow down journal writes (...and triggers a premature mirror failover because of it).
4. You definitely need to use the ExternalFreeze/Thaw APIs to ensure the CACHE.DATs within the snapshot are "clean".
5. Confirm your current Q0S timeout value as some earlier versions of Caché had a very low QoS value and with snapshots I believe it should be 8 set to seconds and not to exceed 30 seconds.
Also the links that Peter mentioned are very good links to reference as well for more details.
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